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dc.contributor.authorSmyth, Mike
dc.date.accessioned2020-02-12T13:26:48Z
dc.date.available2020-02-12T13:26:48Z
dc.date.issued2012-01
dc.identifier.citationSmyth, M., 2012. PaRAMeDIC: a randomized controlled trial of a mechanical compression device. Journal of Paramedic Practice, 4 (1), 28-33.en_US
dc.identifier.issn1759-1376
dc.identifier.issn2041-9457
dc.identifier.doi10.12968/jpar.2012.4.1.28
dc.identifier.urihttp://hdl.handle.net/20.500.12417/780
dc.description.abstractAbstract published with permission. Survival from out-of-hospital cardiac arrest (OHCA) is influenced by the quality of cardiopulmonary resuscitation (CPR). However, research shows that in the out-of-hospital environment, and particularly during ambulance transport, CPR quality is frequently sub-optimal. Mechanical compression devices can deliver high quality CPR, yet there is an absence of high quality evidence to demonstrate improved clinical or cost effectiveness outcomes. The PaRAMeDIC trial will compare manual CPR with mechanical CPR in adult patients with non-traumatic OHCA. Objectives: the primary objective is to evaluate the effectiveness of mechanical chest compressions using the LUCAS (Lund University Cardiopulmonary Assistance System)-2 on mortality at 30 days post-OHCA. Secondary objectives include survived event (return of spontaneous circulation at hospital admission), quality of life and cognitive function at 3 and 12 months, survival at 12 months and cost effectiveness. Method: the trial is a pragmatic, cluster randomized controlled trial. Ambulance vehicles are randomized to control or LUCAS arms. Patient allocation is determined by the first ambulance vehicle which arrives first on scene (manual CPR vehicle or LUCAS CPR vehicle). The trial will assess the clinical and cost effectiveness of the LUCAS-2 device. Trial Registration: The trial is registered on the International Standard Randomised Controlled Trial Number Registry (ISRCTN08233942).
dc.language.isoenen_US
dc.subjectCardiac Arresten_US
dc.subjectLife Support Systemsen_US
dc.subjectParamedicen_US
dc.subjectResuscitationen_US
dc.subjectCardiopulmonary Resuscitationen_US
dc.titlePaRAMeDIC: a randomized controlled trial of a mechanical compression deviceen_US
dc.typeJournal Article/Review
dc.source.journaltitleJournal of Paramedic Practiceen_US
dcterms.dateAccepted2020-01-16
rioxxterms.versionNAen_US
rioxxterms.licenseref.uriAll Rights Reserveden_US
rioxxterms.licenseref.startdate2020-01-16
refterms.panelUnspecifieden_US
refterms.dateFirstOnline2012-01
html.description.abstractAbstract published with permission. Survival from out-of-hospital cardiac arrest (OHCA) is influenced by the quality of cardiopulmonary resuscitation (CPR). However, research shows that in the out-of-hospital environment, and particularly during ambulance transport, CPR quality is frequently sub-optimal. Mechanical compression devices can deliver high quality CPR, yet there is an absence of high quality evidence to demonstrate improved clinical or cost effectiveness outcomes. The PaRAMeDIC trial will compare manual CPR with mechanical CPR in adult patients with non-traumatic OHCA. Objectives: the primary objective is to evaluate the effectiveness of mechanical chest compressions using the LUCAS (Lund University Cardiopulmonary Assistance System)-2 on mortality at 30 days post-OHCA. Secondary objectives include survived event (return of spontaneous circulation at hospital admission), quality of life and cognitive function at 3 and 12 months, survival at 12 months and cost effectiveness. Method: the trial is a pragmatic, cluster randomized controlled trial. Ambulance vehicles are randomized to control or LUCAS arms. Patient allocation is determined by the first ambulance vehicle which arrives first on scene (manual CPR vehicle or LUCAS CPR vehicle). The trial will assess the clinical and cost effectiveness of the LUCAS-2 device. Trial Registration: The trial is registered on the International Standard Randomised Controlled Trial Number Registry (ISRCTN08233942).en_US


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