Paramedic administration of glycoprotein inhibitors for ST elevation myocardial infarction
dc.contributor.author | Dykes, Simon | |
dc.date.accessioned | 2020-01-22T14:33:50Z | |
dc.date.available | 2020-01-22T14:33:50Z | |
dc.date.issued | 2012-08-16 | |
dc.identifier.citation | Dykes, S. 2012. Paramedic administration of glycoprotein inhibitors for ST elevation myocardial infarction. Journal of Paramedic Practice, 4 (3), 155–160. | en_US |
dc.identifier.issn | 1759-1376 | |
dc.identifier.issn | 2041-9457 | |
dc.identifier.doi | 10.12968/jpar.2012.4.3.155 | |
dc.identifier.uri | http://hdl.handle.net/20.500.12417/613 | |
dc.description.abstract | Abstract published with permission. Until recently, paramedics were routinely delivering out-of-hospital thrombolysis for ST segment elevation myocardial infarction (STEMI). Now that primary percutaneous coronary intervention (PPCI) is the favoured reperfusion strategy, STEMI patients are by-passing the local emergency department and taken directly to the catheterisation laboratory via ambulance. STEMI patients within a rural setting are facing the prospect of extended transfer times for reperfusion of an already ischaemic myocardium, a potentially perilous strategy. Empirical research conducted outside the UK has identified that the pre-hospital administration of a glycoprotein inhibitor improves clinical outcome for STEMI patients. Glycoprotein naturally helps to build the fibrin mesh essential within the clotting process. Inhibition of this process by glycoprotein inhibitors IIb/IIIa (GPI IIb/IIIa) prevents aggregation at receptor sites on platelets. Original research supports the notion that GPI IIb/IIIa involvement improves patient clinical outcome for STEMI in the out-of-hospital phase. Paramedics are typically the first contact for the STEMI patient and it is tangible that paramedics have the appropriate skill and knowledge to diagnose the out-of-hospital STEMI. With this in mind, it is the purpose of this article to discuss the use of pre-hospital GPI IIb/IIIa administration and to argue that this intervention should be administered by paramedic personnel. | |
dc.language.iso | en | en_US |
dc.subject | Myocardial Infarction | en_US |
dc.subject | Acute Coronary Syndrome | en_US |
dc.subject | Cardiac Arrest | en_US |
dc.subject | ST Elevation Myocardial Infarction | en_US |
dc.subject | Percutaneous Coronary Intervention | en_US |
dc.title | Paramedic administration of glycoprotein inhibitors for ST elevation myocardial infarction | en_US |
dc.type | Journal Article/Review | |
dc.source.journaltitle | Journal of Paramedic Practice | en_US |
rioxxterms.version | NA | en_US |
rioxxterms.licenseref.uri | http://www.rioxx.net/licenses/all-rights-reserved | en_US |
rioxxterms.licenseref.startdate | 2020-01-16 | |
refterms.panel | Unspecified | en_US |
refterms.dateFirstOnline | 2012-08-16 | |
html.description.abstract | Abstract published with permission. Until recently, paramedics were routinely delivering out-of-hospital thrombolysis for ST segment elevation myocardial infarction (STEMI). Now that primary percutaneous coronary intervention (PPCI) is the favoured reperfusion strategy, STEMI patients are by-passing the local emergency department and taken directly to the catheterisation laboratory via ambulance. STEMI patients within a rural setting are facing the prospect of extended transfer times for reperfusion of an already ischaemic myocardium, a potentially perilous strategy. Empirical research conducted outside the UK has identified that the pre-hospital administration of a glycoprotein inhibitor improves clinical outcome for STEMI patients. Glycoprotein naturally helps to build the fibrin mesh essential within the clotting process. Inhibition of this process by glycoprotein inhibitors IIb/IIIa (GPI IIb/IIIa) prevents aggregation at receptor sites on platelets. Original research supports the notion that GPI IIb/IIIa involvement improves patient clinical outcome for STEMI in the out-of-hospital phase. Paramedics are typically the first contact for the STEMI patient and it is tangible that paramedics have the appropriate skill and knowledge to diagnose the out-of-hospital STEMI. With this in mind, it is the purpose of this article to discuss the use of pre-hospital GPI IIb/IIIa administration and to argue that this intervention should be administered by paramedic personnel. | en_US |