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An investigation to determine whether evidence exists to support the introduction of paralysis agents into the prehospital environment, to assist endotracheal intubation for patients who sustain head injuries

Dady, S.
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Abstract
Head injuries are associated with 50% of all deaths due to trauma, about 5000 deaths annually. In traumatic injury, the brain is exposed to two insults: the initial trauma and the second insult during the body’s response. Prevention of this secondary cerebral insult may improve outcome. Intubation facilitated by rapid sequence induction (RSI) ensures appropriate ventilation, reducing the secondary insult by managing arterial CO2 levels. The existing literature indicates that prehospital RSI does not influence the outcome in patients with multiple trauma, yet fails to examine the effect of RSI and intubation on patient recovery from isolated head injury (IHI). https://emj.bmj.com/content/23/12/e68. This is an Open Access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. http://creativecommons.org/licenses/by-nc/4.0/ DOI http://dx.doi.org/10.1136/emj.2006.041574
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